Teaching & Academics > Science
5.5 h
£19.99 Free for 1 days
Mastering Genetic Engineering: DNA Manipulation & Applications
What you will learn:
- Understand the structure and function of DNA.
- Master advanced DNA manipulation techniques (CRISPR, TALENs, ZFNs).
- Explore the applications of genetic engineering in medicine (gene therapy, personalized medicine).
- Learn about the impact of DNA technology in biotechnology and agriculture.
- Understand the role of DNA analysis in forensic science.
- Develop in-demand skills for a successful career in the field.
Description
Course Overview:
Dive into the exciting world of genetic engineering with our comprehensive course, "Mastering Genetic Engineering: DNA Manipulation & Applications." Uncover the secrets of the genome, from its fundamental structure and function to the cutting-edge techniques used to modify and utilize DNA. This course isn't just theory; we'll explore the practical applications of DNA manipulation across various fields, including revolutionary advancements in medicine, groundbreaking breakthroughs in biotechnology, and the crucial role of DNA in forensic science. Learn to decipher the genetic code, understand advanced techniques like CRISPR-Cas9, and grasp the ethical considerations surrounding genetic engineering.
Key Benefits:
- Decode the Genetic Code: Gain a deep understanding of DNA structure, function, and the intricate language of genes.
- Master DNA Manipulation: Learn advanced techniques such as gene editing (CRISPR-Cas9, TALENs, ZFNs), genome sequencing, and synthetic biology.
- Revolutionize Healthcare: Explore the impact of DNA manipulation on personalized medicine, gene therapy, and drug discovery.
- Transform Industries: Discover how genetic engineering drives innovation in agriculture, bioproduction, and environmental science.
- Advance Forensic Science: Learn the critical role of DNA analysis in criminal investigations and identification.
- Boost Your Career: Develop in-demand skills and knowledge to excel in the rapidly growing field of genetic engineering.
Who Should Enroll?
- Biology and science students seeking advanced knowledge.
- Biologists, geneticists, and researchers aiming to expand their expertise.
- Healthcare professionals interested in personalized and gene therapies.
- Individuals fascinated by genetics and its potential.
- Anyone looking for a career in a cutting-edge scientific field.
Career Paths:
- Genetic Counselor
- Biotechnologist
- Clinical Geneticist
- Forensic DNA Analyst
- Research Scientist
Salary Expectations (Illustrative):
Salaries vary significantly based on experience, location, and specific role. Highly skilled professionals in genetic engineering command competitive salaries globally, with potential for substantial growth in this rapidly evolving field.
Prerequisites:
- Basic biology and genetics knowledge is beneficial.
- Reliable internet access and a computer.
- A passion for learning and scientific exploration.
Curriculum
Course Preview
This introductory section provides a concise overview of the course content, setting the stage for the detailed exploration of DNA and its manipulation that follows. The preview lecture offers a glimpse into what students can expect to learn throughout the course, ensuring they have a clear understanding of the structure and flow of the educational material. This introductory video sets expectations and clarifies the course objectives.
Module 1. Introduction to DNA
This module serves as a foundational introduction to DNA, covering its fundamental concepts and importance. The single lecture in this module provides a comprehensive overview of DNA’s essential characteristics and its role in biological systems, laying the groundwork for the advanced topics discussed in subsequent modules.
Module 2. Structure of DNA
This module delves into the intricate structural details of DNA. Lectures cover the chemical composition of DNA, highlighting the importance of its double helix structure. The genetic code, codons, and genes are explained, providing a comprehensive understanding of how genetic information is encoded and transmitted.
Module 3. Organization of DNA into Chromosomes
This module explores the complex organization of DNA within chromosomes. Lectures cover the various levels of DNA packaging, explaining how the long DNA molecule is efficiently organized within the cell nucleus. The significance of DNA packaging and the structural features of DNA grooves are also discussed in detail.
Module 4. Mitochondrial DNA
This module focuses on mitochondrial DNA, exploring its unique characteristics and inheritance patterns. Lectures cover the introduction to mitochondrial DNA and provide a detailed explanation of mitochondrial inheritance, offering a specialized perspective on DNA's presence and function outside the nucleus.
Module 5. Introduction to DNA Manipulation or Genetic Manipulation
This module introduces the core concept of DNA manipulation or genetic manipulation, laying the groundwork for understanding the advanced techniques discussed in later modules. It explains the various types of genetic manipulation techniques and sets the context for the more advanced concepts.
Module 6. Recombinant DNA technology
This module provides a comprehensive exploration of recombinant DNA technology, tracing its historical development, explaining the process of cloning, and detailing the steps involved in recombinant DNA technology. Various applications are discussed to showcase the practical uses of this powerful technique.
Module 7. DNA libraries
This module focuses on DNA libraries, explaining the creation and use of genomic and cDNA libraries as essential tools in genetic research. The different types of libraries are explained and their roles in various applications are explored.
Module 8. Gene/ Genetic Editing
This module introduces the fundamental concepts of gene editing, covering both the introduction and different types of gene editing techniques, preparing students for a more in-depth exploration of specific techniques in subsequent modules.
Module 9. Zinc-finger nucleases (ZFNs)
This module provides a detailed look at Zinc-finger nucleases (ZFNs), a gene-editing tool. It covers the introduction, structure (domains), steps involved, and applications of ZFNs, providing students with a comprehensive understanding of this gene editing technology.
Module 10. Transcription Activator-Like Effector Nucleases (TALENs)
This module explores Transcription Activator-Like Effector Nucleases (TALENs), another gene editing technology. Lectures cover its introduction, steps involved, and real-world applications, offering a comparison with other gene-editing methods.
Module 11. (CRISPR)-CRISPR-associated protein 9 (Cas9)
This module offers an in-depth examination of CRISPR-Cas9, a revolutionary gene-editing technology. Lectures cover its introduction, structure, historical background, mechanism of action, types of CRISPR systems, steps in genome editing, applications, and challenges, providing a comprehensive understanding of this powerful tool.
Module 12. Applications of Genetic Manipulation
This module explores the diverse applications of genetic manipulation. Topics include GMOs (history, applications, controversies), gene therapy (mechanisms, safety, ethical considerations), CAR T-cell therapy, RNA therapy, and other genetic therapies. This module highlights the real-world impact of genetic engineering.
Module 13. Advances in Genetic Manipulation
This module looks at the cutting-edge advancements and future prospects of genetic manipulation. Topics include future applications, clinical trials, a concluding overview, and future perspectives, concluding the course with a discussion of ongoing developments and potential future breakthroughs.
Module 14. Career Opportunities
This final module provides an overview of career opportunities within the field of genetic engineering, equipping students with knowledge of career paths and potential prospects.
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